Firstaid measures inhalation remove victim to fresh air and keep at rest in a position comfortable for breathing. A wide variety of colloidal silicon dioxide options are available to you, such as grade standard. Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Be sure to use an approvedcertified respirator or equivalent. All spectrum chemical nf, ep grade products are manufactured, packaged and stored under current good manufacturing practices cgmp per 21cfr part 211 in fda registered and inspected facilities.
Some health conditions may make you more susceptible to the sideeffects of the drug. S1510, colloidal silicon dioxide, nf, ep spectrum chemical. Under our main product brand levasil colloidal silica and with our global network of manufacturing facilities, we provide our professional partners with a reliable supply of high and consistent quality colloidal silica. Ac403731500 casno 7631869 synonyms silicon dioxide, synthetic amorphous silica, pyrogenic fumed amorphous silica recommended use laboratory chemicals. Get medical aid if irritation develops or persists.
Section 6 accidental release measures procedures of personal precautions. Silica is another name for the chemical compound composed of silicon and. Learn more on how colloidal silica differs from fumed and other types of silica. When ignited at for 2 hours, it contains not less than 99. Safety data sheet creation date 15dec2011 revision date 30sep2019 revision number 5 1. A safety data sheet will be provided with your first delivery and with subsequent revisions. Colloidal silica based primary binder for investment casting manufacturer. Identification of the substancemixture and of the companyundertaking. A high functionality and multifunctional excipient, it requires less complex processing, has high inherent functionality, and passes that functionality on to the drug formulation. Silicon dioxide is a natural compound of silicon and oxygen found mostly in sand, silica has three main crystalline varieties. The terms hazardous and hazardous materials as used within this sds eu msd should be interpreted as defined by, and accordance with, the osha. Colloidal silicon dioxide 7631869 2315454 not listed ingredient cas number eu einecselincs list eu classification %. Health hazard reactivity spectrum pharmacy products. Colloidal silicon dioxide dried specimen in the crucible for the test for loss on ignition.
Chemtrec usa and canada emergency contact number 1800424. If you experience drowsiness, dizziness, hypotension or a headache as sideeffects when using colloidal silicon dioxide medicine then it may not be safe to drive a vehicle or operate heavy machinery. Silica is another name for silicon oxides, the most prevalent type being sio2. Search results for colloidal silicon dioxide at sigmaaldrich. Prosolv smcc silicified microcrystalline cellulose jrs pharma. Colloidal silicon dioxide daphnia magna tad ec50 48 hours 14 mgl 24 months rat oral 60 mgkgday noael not carcinogenic. Colloidal silica polishing suspension safety data sheet. Silicon dioxide, single crystal substrate, optical grade, 99. This product has been classified in accordance with the hazard criteria of the canadian controlled products. At levasil colloidal silica we contribute to your success with innovations in silica chemistry. Colloidal silicon dioxide 112945525 15 designates that a specific chemical identity andor percentage of composition has been withheld as a trade secret. Silicon dioxide sio2, or silica, is known in nature as sand or quartz.
In many parts of the world, silica is the major constituent of sand. Vinyl acetate vapor may react vigorously in contact with silica gel. Prosolv smcc, silicified microcrystalline cellulose, is a unique combination of microcrystalline cellulose mcc and colloidal silicon dioxide csd. Chemtrec usa and canada emergency contact number 1. Safety data sheet according to 19072006ec, article 31. Conditions for safe storage, including any incompatibilities. This product has been classified in accordance with the hazard criteria of the cpr and the msds contains all of the information required by the cpr. Uses advised against food, drug, pesticide or biocidal. Before using colloidal silicon dioxide, inform your doctor about your current list of medications, over the counter products e. This material safety data sheet msds applies only to the material as packaged.
Sigmaaldrich offers a number of silicon dioxide products. Should the product become dried or misted such that inhalation of the material is possible, standard hygiene practices should be utilized to ensure that exposure to respirable particles is within the regulated limits. Proprietary ingredients indicated as hazardous have been assessed under standards for workplace safety. Preparation and characterization of silicon dioxide. Product is noncombustible hazardous combustion products. Impervious gloves are recommended if skin contact with drug product is possible and for bulk processing operations.
Colloidal silicon dioxide is a submicroscopic fumed silica prepared by the vaporphase hydrolysis of a silicon compound. Colloidal silicon dioxide daphnia magna tad ec50 48 hours 14 mgl 24 months rat. Colloidal silicon dioxide, nf, ep is used both in the food and pharmaceutical industries as a powder flow helper in the production of tablets. This product has been classified in accordance with the hazard criteria of the controlled products regulations and the msds contains all of the information required by those regulations. Wear safety glasses or goggles if eye contact is possible. Silica, colloidal anhydrous silicia colloidalis anhydrica aerosil contd. Manufacture of aerosil and aeroperl pharma colloidal silicon dioxide 6 2. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a warranty or quality specification. Silicosis is a chronic disease of the lungs that is caused by the inhalation of silica dust over long period of time. Carbon dioxide, dry chemical powder, or appropriate foam. Special remarks on reactivity special remarks on corrosivity polymerization will not occur. Silicon dioxide cas 7631869 colloidal, highly dispersed emprove essential ph eur,nf,jp,e 551 find msds or sds, a coa, data sheets and more information. Colloidal silicon dioxide 7631869 2315454 titanium dioxide 463677 2366755.
D2b this product contains trace amounts of 1, 3 butadiene, a chemical known to the state of california to cause cancer. The information provided in this safety data sheet is correct to the best of our knowledge, information and belief at the date of its publication. Product and company identification product identifier. Material safety data sheet according to regulation ec no.
Safety data sheet according to 19072006ec, article 31 trade name. Impervious protective clothing is recommended if skin contact with drug product is possible and for bulk processing operations. Silicon dioxide, chemically preparednot a pbt, vpvb substance as per the criteria of the. Silicon dioxide, amorphous gel, 30% in isopropanol safety data sheet 08142015 en english us sds id. It is widely used in creams and lotions as a suspending agent and opacifier. You might have seen it on a label or two and wondered what it is exactly. This product contains amorphous, colloidal or fumed silica. Call 310 5168000 all chemicals may pose unknown hazards and should be used with caution. Appropriate engineering controls engineering measures to reduce exposure. Silicon dioxide, amorphous gel, 30% in isopropanol safety. Definition colloidal silicon dioxide is a submicroscopic fumed silica prepared by the vaporphase hydrolysis of a silicon compound. Silica is one of the most complex and most abundant families of materials, existing as a compound of several minerals and as synthetic product.
Ingestion of this material can cause effects similar to those seen in clinical use including cholinergic crisis, charactertized by severe nausea, vomiting, salivation, sweating, slow heart rate, low blood pressure, muscles weakness, respiratory depression, syncope and convulsions. Also known as colloidal silica, this agent finds itself into many food and medicine products. Levasil colloidal silica a natural part of everyday life. Do not attempt to take action without suitable protective equipment. About 52% of these are oxide, 17% are electronics chemicals, and 7% are adsorbent. Colloidal silica suspension allied high tech products, inc. Colloidal silicon dioxide 7631869 2315454 not listed not listed microcrystalline cellulose 9004346 2326749 not listed not listed additional information. Fine particulate silica dust from quartz rock causes over a longterm progressive lung injury, silicosis. Sigmaaldrich material safety data sheet date printed. Silica, hydrophobic colloidal silica hydrophobica colloidalis definition colloidal silicon dioxide partly alkylated for hydrophobation. Silicon dioxide msds, silicon dioxide materials safety.
A graphic model of aerosil pharma colloidal silicon dioxide aggregates. Glasses are a class of materials made from silicon dioxide and other metal oxides. Aerosil colloidal silicon dioxide for pharmaceuticals recommended products. In veterinary applications, it functions as a topical and g. Incompatible with fluoride, oxygen, difluoride, chlorine trifluoride. Pfizer inc believes that the information contained in this material safety data sheet is accurate. Use fullface self contained breathing apparatus, impervious protective clothing. However, the data is provided without any warranty, expressed or implied, regarding its correctness or accuracy.
Silicon dioxide, synthetic amorphous silica, pyrogenic silica, hydrophobic fumed silica. S1510, colloidal silicon dioxide, nf, ep table of contents product specification safety data sheet sds manufacturer certification of quality management system qms certification of current good manufacturing practices cgmp product bsetse statement product allergen statement product aflatoxin statement. Call a poison center or doctorphysician if you feel unwell. Aerosil and aeroperl pharma colloidal silicon dioxide 3 the optimal glidant and beyond 2. Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. Discover our broad product portfolio and reliable supply. Wear selfcontained breathing apparatus and protective clothing to prevent contact with skin and eyes. Aerosil colloidal silicon dioxide for pharmaceuticals. Aerosil and aeroperl pharma colloidal silicon dioxide. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. The information in silicon dioxide e551 msds was obtained from current and reliable sources.
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